Kelly E Dooley Selected Research

Pyrazinamide

1/2022	Novel Regimens of Bedaquiline-Pyrazinamide Combined with Moxifloxacin, Rifabutin, Delamanid and/or OPC-167832 in Murine Tuberculosis Models.
1/2021	Pretomanid Pharmacokinetics in the Presence of Rifamycins: Interim Results from a Randomized Trial among Patients with Tuberculosis.
1/2021	Optimising pyrazinamide for the treatment of tuberculosis.
1/2021	Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis.
1/2020	Population Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Pregnant South African Women with Tuberculosis and HIV.
1/2019	Alternative dosing guidelines to improve outcomes in childhood tuberculosis: a mathematical modelling study.
10/2018	Suboptimal Antituberculosis Drug Concentrations and Outcomes in Small and HIV-Coinfected Children in India: Recommendations for Dose Modifications.
1/2017	Population Pharmacokinetics of Pyrazinamide in Patients with Tuberculosis.
1/2016	A Phase 2 Randomized Trial of a Rifapentine plus Moxifloxacin-Based Regimen for Treatment of Pulmonary Tuberculosis.
2/2015	Daily rifapentine for treatment of pulmonary tuberculosis. A randomized, dose-ranging trial.

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Kelly E Dooley Research Topics

Disease

58	Tuberculosis (Tuberculoses) 09/2022 - 06/2002
19	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 10/2022 - 08/2012
12	Pulmonary Tuberculosis 01/2022 - 02/2011
9	HIV Infections (HIV Infection) 12/2020 - 06/2010
6	Coinfection 01/2022 - 04/2012
5	Meningeal Tuberculosis (Tuberculous Meningitis) 10/2022 - 01/2017
4	Acquired Immunodeficiency Syndrome (AIDS) 12/2021 - 04/2012
4	Infections 11/2021 - 06/2010
4	Body Weight (Weight, Body) 01/2021 - 01/2015
3	Immune Reconstitution Inflammatory Syndrome 01/2022 - 01/2017
3	Extensively Drug-Resistant Tuberculosis 01/2021 - 01/2019
3	Hearing Loss (Hearing Impairment) 06/2020 - 01/2019
2	Lung Diseases (Lung Disease) 11/2021 - 01/2018
2	Ototoxicity 06/2020 - 01/2019
2	Deafness (Deaf Mutism) 01/2020 - 01/2019
1	Opportunistic Infections (Opportunistic Infection) 01/2022
1	Persistent Infection 01/2021
1	Hypertension (High Blood Pressure) 01/2020
1	Latent Tuberculosis 01/2020
1	Hypoalbuminemia 01/2019
1	Latent Infection 01/2019
1	Infant Death 01/2018
1	Inflammation (Inflammations) 10/2017
1	Hypoxia (Hypoxemia) 10/2017
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2017
1	Granuloma 09/2015
1	Hypersensitivity (Allergy) 01/2015
1	Buruli Ulcer 01/2011
1	Bacterial Infections (Bacterial Infection) 12/2003
1	Dyspnea (Shortness of Breath) 06/2002
1	Bacterial Pneumonia 06/2002
1	Pneumonia (Pneumonitis) 06/2002

Drug/Important Bio-Agent (IBA)

42	Pharmaceutical PreparationsIBA 09/2022 - 06/2010
23	Rifampin (Rifampicin)FDA LinkGeneric 10/2022 - 01/2011
16	Isoniazid (Ftivazide)FDA LinkGeneric 01/2022 - 08/2012
14	bedaquiline (R207910)IBA 10/2022 - 06/2010
14	rifapentine (Priftin)FDA Link 09/2022 - 06/2014
11	Pyrazinamide FDA LinkGeneric 01/2022 - 08/2012
10	RifamycinsIBA 01/2022 - 11/2014
8	efavirenz (Sustiva)FDA Link 09/2022 - 04/2012
6	dolutegravirIBA 01/2022 - 01/2020
5	OPC-67683IBA 10/2022 - 10/2019
5	Moxifloxacin (Avelox)FDA Link 09/2022 - 01/2016
5	Ethambutol (Myambutol)FDA LinkGeneric 01/2021 - 02/2015
5	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 10/2017
4	pretomanidIBA 02/2021 - 01/2020
3	FluoroquinolonesIBA 01/2022 - 06/2002
3	Linezolid (Zyvox)FDA Link 01/2021 - 01/2020
3	AminoglycosidesIBA 06/2020 - 01/2019
2	Levofloxacin (Levaquin)FDA Link 10/2022 - 01/2018
2	Meropenem (Merrem)FDA LinkGeneric 01/2022 - 01/2021
2	NitroimidazolesIBA 01/2022 - 01/2021
2	Rifabutin (Ansamycin)FDA Link 01/2022 - 01/2021
2	CreatinineIBA 01/2021 - 01/2020
2	TabletsIBA 01/2019 - 01/2018
2	Antitubercular AgentsIBA 01/2019 - 01/2016
1	bictegravirIBA 01/2022
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 01/2022
1	Integrase InhibitorsIBA 01/2022
1	IntegrasesIBA 01/2022
1	cabotegravirIBA 01/2022
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2022
1	AlbuminsIBA 01/2022
1	AcetyltransferasesIBA 12/2021
1	Imipenem FDA Link 11/2021
1	DiarylquinolinesIBA 11/2021
1	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 10/2021
1	Contraceptive Agents (Contraceptives)IBA 10/2021
1	9 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA 08/2021
1	APTIBA 01/2021
1	Reverse Transcriptase InhibitorsIBA 01/2020
1	NucleosidesIBA 01/2020
1	Serum AlbuminIBA 01/2020
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2019
1	AntioxidantsIBA 01/2019
1	Vitamin B 6IBA 01/2017
1	SteroidsIBA 01/2017
1	Ofloxacin (Ofloxacine)FDA LinkGeneric 10/2015
1	Verapamil (Calan)FDA LinkGeneric 01/2015
1	Dihydrotachysterol (AT 10)IBA 01/2015
1	Ritonavir (Norvir)FDA Link 11/2014
1	Lopinavir FDA Link 11/2014
1	Nevirapine (Viramune)FDA Link 11/2014
1	beta-LactamsIBA 05/2013
1	Clofazimine (Lamprene)FDA Link 05/2013
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 04/2012
1	Investigational DrugsIBA 01/2012
1	Streptomycin (Streptomycin Sulfate)FDA Link 01/2011

Therapy/Procedure

17	Therapeutics 01/2022 - 06/2002
4	Duration of Therapy 01/2021 - 06/2014
3	Injections 10/2021 - 08/2012
3	Drug Therapy (Chemotherapy) 03/2017 - 02/2015
2	Art Therapy 01/2018 - 01/2017
1	Precision Medicine 01/2022
1	Retreatment 02/2011